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Article

Bedaquiline Resistance: Its Emergence, Mechanism, and Prevention

7 Nov 2017

Abstract excerpt

Bedaquiline, a new antituberculosis drug, has already been used in >50 countries. The emergence of bedaquiline resistance is alarming, as it may result in the rapid loss of this new drug. This article aims to review currently identified mechanisms of resistance and the emergence of bedaquiline resistance, and discuss strategies to delay the resistance acquisition. In vitro and clinical studies as well as reports...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29126225
DOI: 10.1093/cid/cix992

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