Article
Evaluating the glucose raising effect of established loci via a genetic risk score.
PloS one - 1 Jan 2017
Marouli Eirini, Kanoni Stavroula, Mamakou Vasiliki, Hackinger Sophie, Southam Lorraine, Prins Bram, Rentari Angela, Dimitriou Maria, Zengini Eleni, Gonidakis Fragiskos, Kolovou Genovefa, Kontaxakis Vassilis, Rallidis Loukianos, Tentolouris Nikolaos, Thanopoulou Anastasia, Lamnissou Klea, Dedoussis George, Zeggini Eleftheria, Deloukas Panagiotis
Abstract excerpt
Recent genome-wide association studies have identified several single nucleotide polymorphisms (SNPs) associated with glucose levels. We tested the hypothesis here whether the cumulative effect of glucose raising SNPs, assessed via a score, is associated with glucose levels. A total of 1,434 participants of Greek descent from the THISEAS study and 1,160 participants form the GOMAP study were included in this...
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