Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Implications of aging and the endoplasmic reticulum unfolded protein response on the molecular modality of breast cancer

1 Nov 2017

Abstract excerpt

The endoplasmic reticulum (ER) is an important subcellular organelle that is involved in numerous activities required to achieve and maintain functional proteins in addition to its role in the biosynthesis of lipids and as a repository of intracellular Ca2+. The inability of the ER to cope with protein folding beyond its capacity causes disturbances that evoke ER stress. Cells possess molecular mechanisms aimed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Endoplasmic Reticulum Stress and Disease
Share to Sirtuins and Resveratrol in Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29123254
DOI: 10.1038/emm.2017.215

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Implications of aging and the endoplasmic reticulum unfolded protein response on the molecular modality of breast cancerPMID 29123254Read ↗

Unfolding the Role of Stress Response Signaling in Endocrine Resistant Breast CancersSemantic proximity Read ↗

Decoding contextual crosstalk: revealing distinct interactions between non-coding RNAs and unfolded protein response in breast cancerSemantic proximity Read ↗

Targeting protein quality control pathways in breast cancerSemantic proximity Read ↗

Endoplasmic Reticulum Stress and CancerSemantic proximity Read ↗

The role of the unfolded protein response in cancer progression: From oncogenesis to chemoresistanceSemantic proximity Read ↗

Novel roles of the unfolded protein response in the control of tumor development and aggressiveness.Semantic proximity Read ↗

Endoplasmic reticulum proteostasis: a key checkpoint in cancerSemantic proximity Read ↗

How the Unfolded Protein Response Is a Boon for Tumors and a Bane for the Immune SystemSemantic proximity Read ↗

The Unfolded Protein Response in Health and DiseaseSemantic proximity Read ↗

Dual role of Endoplasmic Reticulum Stress-Mediated Unfolded Protein Response Signaling Pathway in CarcinogenesisSemantic proximity Read ↗

Endoplasmic Reticulum Stress, Unfolded Protein Response, and Cancer Cell FateSemantic proximity Read ↗

The unfolded protein response and cellular senescence. A review in the theme: cellular mechanisms of endoplasmic reticulum stress signaling in health and disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.