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Unfolding the Role of Stress Response Signaling in Endocrine Resistant Breast Cancers

22 Jun 2015

Abstract excerpt

The unfolded protein response (UPR) is an ancient stress response that enables a cell to manage the energetic stress that accompanies protein folding. There has been a significant recent increase in our understanding of the UPR, how it integrates physiological processes within cells, and how this integration can affect cancer cells and cell fate decisions. Recent publications have highlighted the role of UPR...

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PMID: 26157705
DOI: 10.3389/fonc.2015.00140

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