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Paving the Path toward Porcine Organs for Transplantation

8 Nov 2017

Abstract excerpt

The pig heart is a candidate organ for xenotransplantation, but endogenous retroviruses (ERVs) in the pig genome can infect human cells in vitro, raising the specter of zoonotic infection. A recent report describes the generation of healthy pigs free of replication-competent ERVs.

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Identifiers

PMID: 29117497
DOI: 10.1056/nejmcibr1710853

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