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Pig endogenous retroviruses and xenotransplantation

7 Jun 2002

Abstract excerpt

Xenotransplantation of porcine organs might provide an unlimited source of donor organs to treat endstage organ failure diseases in humans. However, pigs harbour retroviruses with unknown pathogenic potential as an integral part of their genome. While until recently the risk of interspecies transmission of these porcine endogenous retroviruses (PERV) during xenotransplantation has been thought to be negligible,...

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PMID: 12060460
DOI: 10.1034/j.1399-3089.2002.01110.x

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