Article
Lung epithelial response to cigarette smoke and modulation by the nicotinic alpha 7 receptor.
PloS one - 1 Jan 2017
Gahring Lorise C, Myers Elizabeth J, Dunn Diane M, Weiss Robert B, Rogers Scott W
Abstract excerpt
Cigarette smoking (CS) is a principal contributor to a spectrum of devastating lung diseases whose occurrence and severity may vary between individuals and not appear for decades after prolonged use. One explanation for the variability and delay in disease onset is that nicotine, the addictive component of CS, acts through the ionotropic nicotinic acetylcholine receptor (nAChR) alpha7 (α7) to modulate...
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