Article
Exploring venlafaxine pharmacokinetic variability with a phenotyping approach, a multicentric french-swiss study (MARVEL study).
BMC pharmacology & toxicology - 7 Nov 2017
Lloret-Linares Célia, Daali Youssef, Chevret Sylvie, Nieto Isabelle, Molière Fanny, Courtet Philippe, Galtier Florence, Richieri Raphaëlle-Marie, Morange Sophie, Llorca Pierre-Michel, El-Hage Wissam, Desmidt Thomas, Haesebaert Frédéric, Vignaud Philippe, Holtzmann Jerôme, Cracowski Jean-Luc, Leboyer Marion, Yrondi Antoine, Calvas Fabienne, Yon Liova, Le Corvoisier Philippe, Doumy Olivier, Heron Kyle, Montange Damien, Davani Siamak, Déglon Julien, Besson Marie, Desmeules Jules, Haffen Emmanuel, Bellivier Frank
Abstract excerpt
BACKGROUND: It is well known that the standard doses of a given drug may not have equivalent effects in all patients. To date, the management of depression remains mainly empirical and often poorly evaluated. The development of a personalized medicine in psychiatry may reduce treatment failure, intolerance or resistance, and hence the burden and costs of mood depressive disorders. The Geneva Cocktail Phenotypic...
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