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Article

Non‐random reassortment in human influenza A viruses

1 Jan 2008

Abstract excerpt

BACKGROUND: The influenza A virus has two basic modes of evolution. Because of a high error rate in the process of replication by RNA polymerase, the viral genome drifts via accumulated mutations. The second mode of evolution is termed a shift, which results from the reassortment of the eight segments of this virus. When two different influenza viruses co-infect the same host cell, new virions can be released...

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PMID: 19453489
DOI: 10.1111/j.1750-2659.2007.00030.x

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