Article
EGFR mutation status and survival after diagnosis of brain metastasis in nonsmall cell lung cancer.
Neuro-oncology - 1 Nov 2010
Eichler April F, Kahle Kristopher T, Wang Daphne L, Joshi Victoria A, Willers Henning, Engelman Jeffrey A, Lynch Thomas J, Sequist Lecia V
Abstract excerpt
A small subset of patients with nonsmall cell lung cancer (NSCLC) harbors mutations in the epidermal growth factor receptor (EGFR) that predict unique sensitivity to EGFR tyrosine kinase inhibitors (TKIs). The characteristics and behavior of brain metastases (BMs) in these patients have not been well described. The longitudinal records of all NSCLC patients who underwent EGFR mutation screening at our center from...
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