Article
EGFR mutations are associated with favorable intracranial response and progression-free survival following brain irradiation in non-small cell lung cancer patients with brain metastases.
Radiation oncology (London, England) - 30 Oct 2012
Lee Hsin-Lun, Chung Tao-Sang, Ting Lai-Lei, Tsai Jo-Ting, Chen Shang-Wen, Chiou Jeng-Fong, Leung Henry Wing-Cheung, Liu H Eugene
Abstract excerpt
BACKGROUND: The presence of epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC) is associated with increased radiosensitivity in vitro. However, the results from clinical studies regarding the radiosensitivity in NSCLC with mutant EGFR are inconclusive. We retrospectively analyzed our NSCLC patients who had been regularly followed up by imaging studies after irradiation for...
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