Article
The PCSK9 decade.
Journal of lipid research - 1 Dec 2012
Lambert Gilles, Sjouke Barbara, Choque Benjamin, Kastelein John J P, Hovingh G Kees
Abstract excerpt
PCSK9 proprotein convertase subtilisin/kexin type (PCSK9) is a crucial protein in LDL cholesterol (LDL-C) metabolism by virtue of its pivotal role in the degradation of the LDL receptor. In recent years, both in vitro and in vivo studies have greatly supplemented our understanding of the (patho)physiological role of PCSK9 in human biology. In the current review, we summarize studies published or in print before...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
