Article
A novel mechanism to explain protein abnormalities in schizophrenia based on the flavivirus resistance gene.
Molecular psychiatry - 1 Nov 2001
Brown J S
Abstract excerpt
The geographical distribution of schizophrenia was previously shown to correlate with the global distribution of tick-borne flaviviruses. The correlation suggests a natural resistance gene to flaviviruses could be involved in schizophrenia. The flavivirus resistance gene, Flv, a gene found in wild mice and certain in-bred strains, confers resistance to flaviviruses through the interaction of cellular proteins...
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