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Article

Mapping genomic and transcriptomic alterations spatially in epithelial cells adjacent to human breast carcinoma.

Nature communications - 1 Nov 2017

Abdalla Moustafa, Tran-Thanh Danh, Moreno Juan, Iakovlev Vladimir, Nair Ranju, Kanwar Nisha, Abdalla Mohamed, Lee Jennifer P Y, Kwan Jennifer Yin Yee, Cawthorn Thomas R, Warren Keisha, Arneson Nona, Wang Dong-Yu, Fox Natalie S, Youngson Bruce J, Miller Naomi A, Easson Alexandra M, McCready David, Leong Wey L, Boutros Paul C, Done Susan J

Abstract excerpt

Almost all genomic studies of breast cancer have focused on well-established tumours because it is technically challenging to study the earliest mutational events occurring in human breast epithelial cells. To address this we created a unique dataset of epithelial samples ductoscopically obtained from ducts leading to breast carcinomas and matched samples from ducts on the opposite side of the nipple. Here, we...

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Share to Carcinoma, Ductal, Breast
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29093438
DOI: 10.1038/s41467-017-01357-y
PMCID: PMC5665998

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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