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The molecular pathology of breast cancer progression

14 Oct 2010

Abstract excerpt

The current model of human breast cancer progression proposes a linear multi-step process which initiates as flat epithelial atypia (FEA), progresses to atypical ductal hyperplasia (ADH), evolves into DCIS and culminates in the potentially lethal stage of invasive ductal carcinoma. For several decades a major challenge to human breast cancer research has been the identification of the molecular alterations...

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PMID: 21125683
DOI: 10.1002/path.2808

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