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Article

Social behavior in Fmr1 knockout mice carrying a human FMR1 transgene.

Behavioral neuroscience - 1 Jun 2008

Spencer Corinne M, Graham Deanna F, Yuva-Paylor Lisa A, Nelson David L, Paylor Richard

Abstract excerpt

Fragile X syndrome (FXS) results from the loss of expression of the fragile X mental retardation (FMR1) gene. Individuals affected by FXS experience many behavioral problems, including cognitive impairment, hyperactivity, social anxiety, and autistic-like behaviors. A mouse model of Fmr1 deficiency (Fmr1KO) exhibits several similar behavioral phenotypes, including alterations in social behavior. In an earlier...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18513141
DOI: 10.1037/0735-7044.122.3.710

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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