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Human Endogenous Retrovirus-K and TDP-43 Expression Bridges ALS and HIV Neuropathology

11 Oct 2017

Abstract excerpt

Despite the repetitive association of endogenous retroviruses in human disease, the mechanisms behind their pathological contributions remain to be resolved. Here we discuss how neuronal human endogenous retrovirus-K (HERV-K) expression in human immunodeficiency virus (HIV)-infected individuals is a distinct pathological aspect of HIV-associated neurological conditions, such as HIV encephalitis and HIV-associated...

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PMID: 29075249
DOI: 10.3389/fmicb.2017.01986

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