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Article

2SNP heritability and effects of genetic variants for neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio.

Journal of human genetics - 1 Nov 2017

Lin Bochao Danae, Carnero-Montoro Elena, Bell Jordana T, Boomsma Dorret I, de Geus Eco J, Jansen Rick, Kluft Cornelis, Mangino Massimo, Penninx Brenda, Spector Tim D, Willemsen Gonneke, Hottenga Jouke-Jan

Abstract excerpt

Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are important biomarkers for disease development and progression. To gain insight into the genetic causes of variance in NLR and PLR in the general population, we conducted genome-wide association (GWA) analyses and estimated SNP heritability in a sample of 5901 related healthy Dutch individuals. GWA analyses identified a new genome-wide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29066854
DOI: 10.1038/jhg.2017.76
PMCID: PMC5669488

Genes

ARHGEF3
BAK1
MYB
PSMD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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