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Article

Negative Correlation Between Hepatitis C Virus (HCV) and Let-7 MicroRNA Family in Transplanted Livers: The Role of rs868 Single-Nucleotide Polymorphism.

Annals of transplantation - 24 Oct 2017

Sajjad Emir Ahmed, Radkowski Marek, Perkowska-Ptasińska Agnieszka, Pacholczyk Marek, Durlik Magdalena, Fedorowicz Mikołaj, Pietrzak Renata, Ziarkiewicz-Wróblewska Bogna, Włodarski Paweł, Malejczyk Jacek

Abstract excerpt

BACKGROUND Genetic alterations of TGF-β pathway members, including its transmembrane receptor, TGFBR1, may influence the course of HCV infection. Rs868 is a single-nucleotide polymorphism of the 3'UTR region of TGFBR1, located in a binding site for the conserved let-7/miR98 microRNA family. Previously, we demonstrated a favorable course of hepatitis C recurrence after liver transplantation in rs868 AG genotype of...

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Identifiers

PMID: 29061957
DOI: 10.12659/aot.905540
PMCID: PMC6248281

Genes

TGFBR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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