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Article

IL-17 signalling restructures the nasal microbiome and drives dynamic changes following Streptococcus pneumoniae colonization.

BMC genomics - 23 Oct 2017

Ritchie Neil D, Ijaz Umer Z, Evans Tom J

Abstract excerpt

BACKGROUND: The bacterial pathogen Streptococcus pneumoniae colonizes the nasopharynx prior to causing disease, necessitating successful competition with the resident microflora. Cytokines of the IL-17 family are important in host defence against this pathogen but their effect on the nasopharyngeal microbiome is unknown. Here we analyse the influence of IL-17 on the composition and interactions of the...

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Identifiers

PMID: 29058583
DOI: 10.1186/s12864-017-4215-3
PMCID: PMC5651609

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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