Article
Inferred father-to-son transmission of herpes simplex virus results in near-perfect preservation of viral genome identity and in vivo phenotypes.
Scientific reports - 20 Oct 2017
Pandey Utsav, Renner Daniel W, Thompson Richard L, Szpara Moriah L, Sawtell Nancy M
Abstract excerpt
High throughout sequencing has provided an unprecedented view of the circulating diversity of all classes of human herpesviruses. For herpes simplex virus 1 (HSV-1), we and others have previously published data demonstrating sequence diversity between hosts. However the extent of variation during transmission events, or in one host over years of chronic infection, remain unknown. Here we present an initial...
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