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Article

Comparative Genomics of Herpes Simplex Virus 2 Isolated from a Maternal-Neonatal Dyad Reveals High Consensus Sequence Homology as Well as Minor Variant Diversity.

Journal of the Pediatric Infectious Diseases Society - 4 Aug 2026

Abu Rass Reem, Simons Lacy M, Bowen Christopher D, Carter Haley S, Renner Daniel W, Szpara Moriah L, Akhtar Lisa N

Abstract excerpt

Neonatal herpes simplex virus disease most often occurs following mother-to-neonate transmission during childbirth. However, genomic differences between the maternal and neonatal viral populations are poorly understood. Here, we performed deep whole-genome sequencing of clinical HSV-2 samples obtained from a maternal-neonatal dyad to investigate viral population dynamics during transmission. Newborns can become...

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Share to Consensus Sequence
Share to Genome, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Herpes Genitalis

Share to Herpes Simplex

Share to Herpesvirus 2, Human

Share to Infectious Disease Transmission, Vertical

Share to Pregnancy Complications, Infectious

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Source

Identifiers

PMID: 42497092
DOI: 10.1093/jpids/piag064

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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