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Article

Two novel GCK mutations in Chinese patients with maturity-onset diabetes of the young.

Endocrine - 1 Jan 2024

Wang Tao, Zhu Mengmeng, Wang Yun, Hu Cheng, Fang Chen, Hu Ji

Abstract excerpt

PURPOSE: Heterozygous inactivating mutations in the glucokinase (GCK) gene result in the asymptomatic fasting hyperglycemia named as GCK-MODY or MODY2. The genetic testing can effectively avoid the misdiagnosis and inappropriate treatment for GCK-MODY. METHODS: A total of 25 unrelated families with MODY were screened for mutations in coding region of GCK by using direct sequencing. Three different bioinformatics...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37847371
DOI: 10.1007/s12020-023-03509-1

Genes

GCK
F3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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Two novel GCK mutations in Chinese patients with maturity-onset diabetes of the young.PMID 37847371Read ↗

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[A three-year follow-up observation of a pedigree of maturity onset diabetes of the young caused by a novel mutation of glucokinase and literature review].Semantic proximity Read ↗

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