Article
Genetic analysis of deep phenotyping projects in common disorders.
Schizophrenia research - 1 May 2018
Gershon Elliot S, Pearlson Godfrey, Keshavan Matcheri S, Tamminga Carol, Clementz Brett, Buckley Peter F, Alliey-Rodriguez Ney, Liu Chunyu, Sweeney John A, Keedy Sarah, Meda Shashwath A, Tandon Neeraj, Shafee Rebecca, Bishop Jeffrey R, Ivleva Elena I
Abstract excerpt
Several studies of complex psychotic disorders with large numbers of neurobiological phenotypes are currently under way, in living patients and controls, and on assemblies of brain specimens. Genetic analyses of such data typically present challenges, because of the choice of underlying hypotheses on genetic architecture of the studied disorders and phenotypes, large numbers of phenotypes, the appropriate...
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