Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

USP7-Specific Inhibitors Target and Modify the Enzyme's Active Site via Distinct Chemical Mechanisms

19 Oct 2017

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Cancer-related Molecular Pathways
Share to Ubiquitin and proteasome pathways

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 29056420
DOI: 10.1016/j.chembiol.2017.09.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

USP7-Specific Inhibitors Target and Modify the Enzyme's Active Site via Distinct Chemical MechanismsPMID 29056420Read ↗

The Multifaceted Roles of USP7: New Therapeutic OpportunitiesSemantic proximity Read ↗

Discovery of Specific Inhibitors of Human USP7/HAUSP Deubiquitinating EnzymeSemantic proximity Read ↗

Structure and function of USP5: Insight into physiological and pathophysiological rolesSemantic proximity Read ↗

USP7: Novel Drug Target in Cancer TherapySemantic proximity Read ↗

Functional Spectrum of USP7 Pathogenic Variants in Hao-Fountain Syndrome: Insights into the Enzyme’s Activity, Stability, and Allosteric ModulationSemantic proximity Read ↗

Small-molecule allosteric activator of ubiquitin-specific protease 7 (USP7)Semantic proximity Read ↗

Functional spectrum of USP7 pathogenic variants in Hao-Fountain syndrome: Insights into the enzyme's activity, stability, and allosteric modulation.Semantic proximity Read ↗

USP7 V517F mutation as a mechanism of inhibitor resistanceSemantic proximity Read ↗

Selective and reversible inhibitors of ubiquitin-specific protease 7: a patent evaluation (WO2013030218)Semantic proximity Read ↗

Nuclear deubiquitination in the spotlight: the multifaceted nature of USP7 biology in diseaseSemantic proximity Read ↗

The key vulnerabilities and therapeutic opportunities in the USP7-p53/MDM2 axis in cancerSemantic proximity Read ↗

USP13: Multiple Functions and Target InhibitionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.