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Article

Mapping eQTL by leveraging multiple tissues and DNA methylation.

BMC bioinformatics - 18 Oct 2017

Acharya Chaitanya R, Owzar Kouros, Allen Andrew S

Abstract excerpt

BACKGROUND: DNA methylation is an important tissue-specific epigenetic event that influences transcriptional regulation of gene expression. Differentially methylated CpG sites may act as mediators between genetic variation and gene expression, and this relationship can be exploited while mapping multi-tissue expression quantitative trait loci (eQTL). Current multi-tissue eQTL mapping techniques are limited to...

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Share to Chromosome Mapping
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 29047346
DOI: 10.1186/s12859-017-1856-9
PMCID: PMC5648503

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LHX9

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