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Article

The roles of Toll-like receptor 4 in the pathogenesis of pathogen-associated biliary fibrosis caused by Clonorchis sinensis.

Scientific reports - 20 Jun 2017

Yan Chao, Li Bo, Fan Fang, Du Ying, Ma Rui, Cheng Xiao-Dan, Li Xiang-Yang, Zhang Bo, Yu Qian, Wang Yu-Gang, Tang Ren-Xian, Zheng Kui-Yang

Abstract excerpt

Pathogen-associated biliary fibrosis (PABF) is a type of liver fibrosis characterized by injuries of cholangiocytes and extra cellular matrix (ECM) deposition around bile ducts caused by various bacteria, fungi, virus and parasites. Recent studies show that TLR4 plays an important role in several other types of liver fibrosis, but the mechanism of TLR4 in PABF is yet really unclear. In the present study, a PABF...

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Identifiers

PMID: 28634394
DOI: 10.1038/s41598-017-04018-8
PMCID: PMC5478609

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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