Article
The UCP2-866G/A Polymorphism Could be Considered as a Genetic Marker of Different Functional Prognosis in Ischemic Stroke After Recanalization.
Neuromolecular medicine - 1 Dec 2017
Díaz-Maroto Cicuéndez I, Fernández-Díaz E, García-García J, Jordán J, Fernández-Cadenas I, Montaner J, Serrano-Heras G, Segura T
Abstract excerpt
Recent studies based on experimental animal models of stroke have suggested that uncoupling protein 2 (UCP2), an inner mitochondrial membrane protein that is thought to regulate energy metabolism and reduce reactive oxygen species generation, provides protection against reperfusion damage. We aimed to investigate whether -866G/A polymorphism in the promoter of the UCP2 gene, which enhances its transcriptional...
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