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Giant variations in giant virus genome packaging

28 Sept 2023

Abstract excerpt

Giant viruses (Nucleocytoviricota) have a largely conserved lifecycle, yet how they cram their large genomes into viral capsids is mostly unknown. The major capsid protein and the packaging ATPase (pATPase) comprise a highly conserved morphogenesis module in giant viruses, yet some giant viruses dispense with an icosahedral capsid, and others encode multiple versions of pATPases, including conjoined ATPase...

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PMID: 37777391
DOI: 10.1016/j.tibs.2023.09.003

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