Article
A single nucleotide polymorphism located in microRNA-499a causes loss of function resulting in increased expression of osbpl1a and reduced serum HDL level.
Oncology reports - 1 Dec 2017
Chen Li-Bo, Zheng Hai-Kuo, Zhang Lei, An Zhe, Wang Xin-Peng, Shan Rui-Ting, Zhang Wen-Qi
Abstract excerpt
Atherosclerosis is the main pathological process that induces CVD (cardiovascular diseases), and the objective of our study was explore whether miR‑499a rs3746444 polymorphism was associated with the HDL level, one of the risk factors of atherosclerosis. Online public miRNA database was utilized...
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