Article
SCD rs41290540 single-nucleotide polymorphism modifies miR-498 binding and is associated with a decreased risk of coronary artery disease.
Molecular genetics & genomic medicine - 1 Mar 2020
Liu Zhou, Yin Xiaojian, Mai Hui, Li Guangning, Lin Zhijun, Jie Wanxin, Li Kanglan, Zhou Haihong, Wei Shouchao, Hu Li, Peng Wanjuan, Lin Jiajing, Yao Feng, Tao Hua, Xiong Xing-Dong, Li Keshen
Abstract excerpt
BACKGROUND: Atherosclerosis is the primary cause of coronary artery disease (CAD), and stearoyl-CoA desaturase (SCD) is associated with atherosclerosis. However, the associations between variants of SCD and CAD have not yet been decided. METHODS: This study analyzed SCD rs41290540 single-nucleotide polymorphism (SNP) in the 3'-untranslated region for an association with a risk of CAD among the Chinese Han...
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