Article
Structure and functional impact of seed region variant in MIR-499 gene family in bronchial asthma.
Respiratory research - 8 Sept 2017
Toraih Eman A, Hussein Mohammad H, Al Ageeli Essam, Riad Eman, AbdAllah Nouran B, Helal Ghada M, Fawzy Manal S
Abstract excerpt
BACKGROUND: Small non-coding RNAs (microRNAs) have been evolved to master numerous cellular processes. Genetic variants within microRNA seed region might influence microRNA biogenesis and function. The study aimed at determining the role of microRNA-499 (MIR-499) gene family polymorphism as a marker for susceptibility and progression of bronchial asthma and to analyze the structural and functional impact of...
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