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Article

In silico assessment of DNA damage response gene variants associated with head and neck cancer.

Journal of biomolecular structure & dynamics - 1 Apr 2023

Das Raima, Kundu Sharbadeb, Laskar Shaheen, Choudhury Yashmin, Ghosh Sankar Kumar

Abstract excerpt

Head and neck cancer (HNC), the sixth most common cancer globally, stands first in India, especially Northeast India, where tobacco usage is predominant, which introduces various carcinogens leading to malignancies by accumulating DNA damages. Consequently, the present work aimed to predict the impact of significant germline variants in DNA repair and Tumour Suppressor genes on HNC development. WES in Ion...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

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Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 35037836
DOI: 10.1080/07391102.2022.2027817

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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