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Article

Specifically differentiated T cell subset promotes tumor immunity over fatal immunity.

The Journal of experimental medicine - 4 Dec 2017

Ramadan Abdulraouf, Griesenauer Brad, Adom Djamilatou, Kapur Reuben, Hanenberg Helmut, Liu Chen, Kaplan Mark H, Paczesny Sophie

Abstract excerpt

Allogeneic immune cells, particularly T cells in donor grafts, recognize and eliminate leukemic cells via graft-versus-leukemia (GVL) reactivity, and transfer of these cells is often used for high-risk hematological malignancies, including acute myeloid leukemia. Unfortunately, these cells also attack host normal tissues through the often fatal graft-versus-host disease (GVHD). Full separation of GVL activity...

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Source

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Identifiers

PMID: 29038366
DOI: 10.1084/jem.20170041
PMCID: PMC5716032

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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