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Article

[CD137 induces vascular muscle cells phenotype transformation through activating nuclear factor of activated T-cells 1 signaling].

Zhonghua xin xue guan bing za zhi - 24 Sept 2017

Zhong W, Li B, Liu J, Xu Y, Chen R, Shao C, Wang Z Q, Yan J C

Abstract excerpt

Objective: To investigate whether CD137 induces primary vascular muscle cells (VSMCs) phenotype transformation through activating nuclear factor of activated T-cells 1(NFATc1) signaling. Methods: VSMCs were obtained from aorta of C57BL/6J mice (8 weeks, male) through tissue-piece inoculating. Cells were divided into control group, CD137 agonist group (treated with CD137L recombinant protein) and anti-CD137 group...

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Source

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PMID: 29036980
DOI: 10.3760/cma.j.issn.0253-3758.2017.09.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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