Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PD-L1 expression in HNPCC-associated colorectal cancer.

Pathology, research and practice - 1 Dec 2017

Shiraliyeva Naila, Friedrichs Jacqueline, Buettner Reinhard, Friedrichs Nicolaus

Abstract excerpt

BACKGROUND: PD-L1 immunohistochemistry is predictive for molecular inhibitors of PD-1/PD-L1 immune checkpoint. Therefore, this study evaluated the PD-L1 expression in patients with Hereditary Non-Polyposis Colorectal Cancer (HNPCC). METHODS: Immunohistochemical expression of PD-L1 in carcinoma cells, stromal macrophages and lymphocytes of 40 HNPCC-patients with colorectal cancer was scored semi-quantitatively....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to B7-H1 Antigen
Share to Carrier Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms

Share to Colorectal Neoplasms, Hereditary Nonpolyposis

Share to DNA Mismatch Repair

Share to MutL Protein Homolog 1

Share to Nuclear Proteins

Source

Identifiers

PMID: 29033182
DOI: 10.1016/j.prp.2017.09.012

Genes

MLH1
MSH2
MSH6
PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

PD-L1 expression in HNPCC-associated colorectal cancer.PMID 29033182Read ↗

Characterisation of PD-L1-positive subsets of microsatellite-unstable colorectal cancers.Semantic proximity Read ↗

PD-L1 Expression in colorectal carcinoma and its correlation with clinicopathological parameters, microsatellite instability and BRAF mutation.Semantic proximity Read ↗

Differences in histological features and PD-L1 expression between sporadic microsatellite instability and Lynch-syndrome-associated disease in Japanese patients with colorectal cancer.Semantic proximity Read ↗

Pathology of Hereditary Nonpolyposis Colorectal CancerSemantic proximity Read ↗

Increased CD8 Tumor Infiltrating Lymphocytes in Colorectal Cancer Microenvironment Supports an Adaptive Immune Resistance Mechanism of PD-L1 Expression.Semantic proximity Read ↗

PD-L1 expression in colorectal cancer is associated with microsatellite instability, BRAF mutation, medullary morphology and cytotoxic tumor-infiltrating lymphocytes.Semantic proximity Read ↗

Role of the pathologist in the diagnosis of hereditary non-polyposis colorectal cancer.Semantic proximity Read ↗

Association of a duodenal follicular lymphoma and hereditary nonpolyposis colorectal cancer.Semantic proximity Read ↗

Expression of Lysosome-Associated Membrane Proteins in Human Colorectal Neoplasms and Inflammatory DiseasesSemantic proximity Read ↗

Accelerated growth of intestinal tumours after radiation exposure in Mlh1-knockout mice: evaluation of the late effect of radiation on a mouse model of HNPCC.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.