Article
Genotyping Strains of Lyme Disease Agents Directly From Ticks, Blood, or Tissue.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018
Barbour Alan G, Cook Vanessa J
Abstract excerpt
The tick-borne spirochetes that cause Lyme disease in North America and Eurasia display strong linkage disequilibrium between certain chromosomal and plasmid loci within each three major geographic areas of their distribution. For strain typing for epidemiologic and ecologic purposes, the commonly used genotypes based on a single locus are the spacer between the 16S-23S ribosomal RNA and the ospC gene of a...
Topics
- Animals
- Arachnid Vectors
- Borrelia burgdorferi
- DNA, Bacterial
- Genetic Loci
- Genotype
- Genotyping Techniques
- Humans
- Linkage Disequilibrium
- Lyme Disease
- Ticks
