Article
KRAS mutation of extraovarian implants of serous borderline tumor: prognostic indicator for adverse clinical outcome.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Feb 2018
Zuo Tao, Wong Serena, Buza Natalia, Hui Pei
Abstract excerpt
In contrast to non-invasive extraovarian implants, invasive implants of ovarian serous borderline tumor/atypical proliferative serous tumor are associated with adverse outcome and have been reclassified as low-grade serous carcinoma. Mutations of KRAS and/or BRAF have been reported in up to 50% of serous borderline tumor/atypical proliferative serous tumor. We investigated KRAS and BRAF mutation frequencies in...
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