Article
Prediction for Intravenous Immunoglobulin Resistance by Using Weighted Genetic Risk Score Identified From Genome-Wide Association Study in Kawasaki Disease.
Circulation. Cardiovascular genetics - 1 Oct 2017
Kuo Ho-Chang, Wong Henry Sung-Ching, Chang Wei-Pin, Chen Ben-Kuen, Wu Mei-Shin, Yang Kuender D, Hsieh Kai-Sheng, Hsu Yu-Wen, Liu Shih-Feng, Liu Xiao, Chang Wei-Chiao
Abstract excerpt
BACKGROUND: Intravenous immunoglobulin (IVIG) is the treatment of choice in Kawasaki disease (KD). IVIG is used to prevent cardiovascular complications related to KD. However, a proportion of KD patients have persistent fever after IVIG treatment and are defined as IVIG resistant. METHODS AND RESULTS: To develop a risk scoring system based on genetic markers to predict IVIG responsiveness in KD patients, a total...
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