Article
Association between P2RY12 Gene Polymorphisms and IVIG Resistance in Kawasaki Patients.
Cardiovascular therapeutics - 1 Jan 2020
Wang Zhouping, Xu Yufen, Zhou Huazhong, Wang Yanfei, Li Wei, Lu Zhaoliang, Jiang Zhiyong, Gu Xueping, Zheng Hao, Zeng Lanlan, Huang Ping, Zhang Li, Gu Xiaoqiong
Abstract excerpt
Children with Kawasaki disease (KD) resistant to intravenous immunoglobulin (IVIG) have a higher incidence of coronary artery lesions (CAL). Despite the association between Purinergic receptor P2Y12 (P2RY12) polymorphism, KD genetic susceptibility, and CAL complications being proved, few studies have assessed the relationship between P2RY12 polymorphisms and IVIG resistance in patients with KD. We recruited 148...
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