Article
Integrin β-3 is required for the attachment, retention and therapeutic benefits of human cardiospheres in myocardial infarction.
Journal of cellular and molecular medicine - 1 Jan 2018
Liu Suyun, Jiang Zhian, Qiao Li, Guo Bingyan, Xiao Wenliang, Zhang Xiaoguang, Chang Liang, Li Yongjun
Abstract excerpt
Cardiovascular diseases remain the leading causes of death worldwide. Stem cell therapy offers a promising option to regenerate injured myocardium. Among the various types of stem cells, cardiosphere cells represent a mixture of intrinsic heart stem cells and supporting cells. The safety and efficacy of cardiosphere cells have been demonstrated in recent clinical trials. Cell-matrix interaction plays an important...
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