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Article

Isolation and expansion of functionally-competent cardiac progenitor cells directly from heart biopsies.

Journal of molecular and cellular cardiology - 1 Aug 2010

Davis Darryl R, Kizana Eddy, Terrovitis John, Barth Andreas S, Zhang Yiqiang, Smith Rachel Ruckdeschel, Miake Junichiro, Marbán Eduardo

Abstract excerpt

The adult heart contains reservoirs of progenitor cells that express embryonic and stem cell-related antigens. While these antigenically-purified cells are promising candidates for autologous cell therapy, clinical application is hampered by their limited abundance and tedious isolation methods. Methods that involve an intermediate cardiosphere-forming step have proven successful and are being tested clinically,...

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Identifiers

PMID: 20211627
DOI: 10.1016/j.yjmcc.2010.02.019
PMCID: PMC2885498

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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