Article
Novel xeno-free human heart matrix-derived three-dimensional scaffolds.
Journal of translational medicine - 18 Jun 2015
Holt-Casper Dolly, Theisen Jeff M, Moreno Alonso P, Warren Mark, Silva Francisco, Grainger David W, Bull David A, Patel Amit N
Abstract excerpt
RATIONALE: Myocardial infarction (MI) results in damaged heart tissue which can progress to severely reduce cardiac function, leading to death. Recent studies have injected dissociated, suspended cardiac cells into coronary arteries to restore function with limited results attributed to poor cell retention and cell death. Extracellular matrix (ECM) injected into damaged cardiac tissue sites show some promising...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
