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Article

Association of ALDH2 rs671 Polymorphism with chronic kidney disease incidence in a population-based Korean cohort.

Scientific reports - 15 Mar 2026

Lee Hyun Jin, Noh Jaekyung, Jeong Seunghwan, Lee Heeyeon, Lee Haekyung, Kim Hyoungnae, Jeon Jin Seok, Noh Hyunjin, Kwon Soon Hyo

Abstract excerpt

The Aldehyde dehydrogenase 2 (ALDH2) rs671 polymorphism, a common variant that impairs aldehyde detoxification, has been linked to cardiovascular disease, but its role in chronic kidney disease (CKD) remains unclear. This study examined the association between the ALDH2 rs671 polymorphism and incident CKD in a population-based cohort, and whether alcohol consumption modifies this relationship. We analyzed 5,369...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alcohol Drinking
Share to Aldehyde Dehydrogenase, Mitochondrial
Share to Cohort Studies
Share to Glomerular Filtration Rate
Share to Incidence
Share to Renal Insufficiency, Chronic
Share to Republic of Korea
Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 41834010
DOI: 10.1038/s41598-026-43186-4
PMCID: PMC13121792

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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