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Article

The DMT1 IVS4+44C>A polymorphism and the risk of iron deficiency anemia in children with celiac disease.

PloS one - 1 Jan 2017

Tolone Carlo, Bellini Giulia, Punzo Francesca, Papparella Alfonso, Miele Erasmo, Vitale Alessandra, Nobili Bruno, Strisciuglio Caterina, Rossi Francesca

Abstract excerpt

BACKGROUND: Iron deficiency anemia in celiac disease is related to impaired duodenal mucosal uptake, due to villous atrophy. Iron enters the enterocytes through an apical divalent metal transporter, DMT1. Different DMT1 transcripts have been identified, depending on the presence of an iron-responsive element that allows DMT1 up-regulation during iron starvation. An intronic DMT1 polymorphism, IVS4+44C>A, has been...

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Identifiers

PMID: 29023457
DOI: 10.1371/journal.pone.0185822
PMCID: PMC5638269

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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