Article
HIV-1 viral load and resistance in genital secretions in patients taking protease-inhibitor-based second-line therapy in Africa.
Antiviral therapy - 1 Jan 2018
Hoppe Anne, Giuliano Marina, Lugemwa Abbas, Thompson Jennifer A, Floridia Marco, Walker Ann S, Senoga Ismail, Abwola Mary C, Pirillo Maria F, Kityo Cissy M, Arenas-Pinto Alejandro, Paton Nicholas I
Abstract excerpt
BACKGROUND: HIV is transmitted primarily through sexual intercourse, and the objective of this study was therefore to assess whether there is occult viral replication and resistance in genital secretions in patients on protease inhibitor (PI)-based second-line therapy. METHODS: HIV-infected adults taking ritonavir-boosted lopinavir with either two nucleoside reverse transcriptase inhibitors (NRTIs), raltegravir...
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