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Article

Porcine Reproductive and Respiratory Syndrome Virus Nonstructural Protein 4 Cleaves Porcine DCP1a To Attenuate Its Antiviral Activity.

Journal of immunology (Baltimore, Md. : 1950) - 15 Oct 2018

Tao Ran, Fang Liurong, Bai Dongcheng, Ke Wenting, Zhou Yanrong, Wang Dang, Xiao Shaobo

Abstract excerpt

As one of the most significant etiological agents in pigs, porcine reproductive and respiratory syndrome virus (PRRSV) has adversely impacted the global swine industry since it was discovered in the 1980s. The mRNA-decapping enzyme 1a (DCP1a), a regulatory factor involved in removing the 5'-methylguanosine cap from eukaryotic mRNA, has recently been identified as an IFN-stimulated gene. However, the role of DCP1a...

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PMID: 30158128
DOI: 10.4049/jimmunol.1701773

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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