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Article

Enhancing GTEx by bridging the gaps between genotype, gene expression, and disease.

Nature genetics - 1 Dec 2017

Abstract excerpt

Genetic variants have been associated with myriad molecular phenotypes that provide new insight into the range of mechanisms underlying genetic traits and diseases. Identifying any particular genetic variant's cascade of effects, from molecule to individual, requires assaying multiple layers of molecular complexity. We introduce the Enhancing GTEx (eGTEx) project that extends the GTEx project to combine gene...

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PMID: 29019975
DOI: 10.1038/ng.3969
PMCID: PMC6636856

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