Article
A Theoretical Model of the Wnt Signaling Pathway in the Epithelial Mesenchymal Transition.
Theoretical biology & medical modelling - 10 Oct 2017
Gasior Kelsey, Hauck Marlene, Wilson Alyson, Bhattacharya Sudin
Abstract excerpt
BACKGROUND: Following the formation of a primary carcinoma, neoplastic cells metastasize by undergoing the epithelial mesenchymal transition (EMT), which is triggered by cues from inflammatory and stromal cells in the microenvironment. EMT allows epithelial cells to lose their highly adhesive nature and instead adopt the spindle-like appearance, as well as the invasive and migratory behavior, of mesenchymal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.