Article
Identification of novel splicing variants of protein tyrosine phosphatase receptor type Z.
Journal of biochemistry - 1 Nov 2017
Fujikawa Akihiro, Chow Jeremy Pak Hong, Matsumoto Masahito, Suzuki Ryoko, Kuboyama Kazuya, Yamamoto Naoki, Noda Masaharu
Abstract excerpt
Protein tyrosine phosphatase receptor type Z (PTPRZ, also known as PTPζ or RPTPβ) is preferentially expressed in the central nervous system (CNS). PTPRZ plays important roles during development and adulthood in CNS myelination, learning and memory. Three splicing isoforms for PTPRZ have been identified to date: two receptor type isoforms, PTPRZ-A and PTPRZ-B, and one secretory isoform, PTPRZ-S. We herein...
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